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Roughly 24 percent of people taking the GLP-1 drug semaglutide (and 11 percent of placebo takers) report constipation, according to the package insert

Clinical efficacy studies of various unimolecular dual and triple agonists targeting the GLP- 1 receptor, GIP receptor, and glucagon receptor have shown promising results when used alone or in conjunction with approved hypoglycemic medications

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