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The amino acid asparagine was first isolated in 1806 from asparagus juice, in which it is abundant (hence its name), and has been found to have an effect on fatigue

This work was partially supported by National Natural Science Foundation of China 81872915 (M.-W.W.), 82073904 (M.-W.W.), 32071203 (L.H.Z), 81922071 (Y.Z.), 81773792 (D.Y.), 81973373 (D.Y.) and 21704064 (Q.T.Z.)

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