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This bacterium plays a critical role in maintaining the gut mucus layer, and its metabolic byproducts stimulate intestinal L-cells to produce GLP-1

A wide range of GLP-1 receptor agonists are currently approved or in clinical development for weight loss or glycemic control

Highmark Blue Cross Blue Shield West Virginia leads commercial market share, followed by The Health Plan, PEIA (the state employee plan), Aetna, and UnitedHealthcare

Gallbladder disease: Rapid weight loss can predispose to gallstones, and some trials (particularly with high-dose semaglutide and liraglutide for obesity) noted a slight increase in gallstone-related events