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Biomarkers of health effects PMI researchers reported a controlled clinical study that applied systems pharmacology and showed that exposure-response gene signature in blood was similarly reduced in smoking cessation or switching to IQOS groups compared to continued smoking 98

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The prestigious British Royal College of Physicians has stated, "the hazard to health arising from long-term vapor inhalation from the e-cigarettes available today is unlikely to exceed 5 percent of the harm from smoking tobacco. Britains Department of Health last year formally endorsed the substitution of e-cigarettes by smokers

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